During or after the attack, the player can take a pill to relieve the symptoms temporarily. If he has run out of pills, then the character will open up his empty bottle, stare at it in disbelief, then pass out, only to wake up in the church in Pala or the medical clinic in the Southern territory. If the player still has medicine, on the final attack, the character will fall to the ground and become immobile until he takes a pill. If he chooses to not take a dose of medicine, he will have 2 or 3 more attacks. In addition, the player is momentarily unable to sprint or jump until the yellow fades. When one happens, the screen will take on a yellowish tint, and everything becomes blurry. The player will get malaria attacks every 30-40 real-life minutes. At the end of the intro, the character will fall forward in the car and pass out as the driver says he looks tired. The character will look at his hands and start coughing as the screen takes on a yellowish tint.
The player character becomes infected with malaria towards the end of the driving intro. Malaria plays a major role in single-player Far Cry 2. Malaria is a mosquito-borne Infectious disease in Far Cry 2.